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This unique virtual learning series taught specific cleanup protocol and safety measures in the event of a hazardous drug spill. Real-life scenarios and procedures were played out using studio-based motion capture actions that were then mapped to custom 3D characters within simulated medical environments. At pivotal junctures, the learner was asked question and prompted to direct safe and effective cleanup procedures, allowing them to take an active role in the simulations and strengthen their retention of core concepts.